Synthesis of sildenafil citrate
Everything appears to be in order. Compound 13a was prepared from compound 12a. Raghava Reddy A.
Preparation of 3-isopropylmethylaminoH-pyrazolecarboxamide 13c. Compound 10b was prepared from 2-hexanone as a pale yellow solid.
Preparation of 3-ethylmethylaminoH-pyrazolecarboxamide 13a. The dichloromethane layer containing compound 3 was taken to the next step as such. Zhang M. Preparation of 3-ethyl 2-ethoxyphenyl methyl-7H-pyrazolo[4,3-d]pyrimidinone 2a.
See also:
Human bonding
Synthesis of sildenafil citrate. A Facile, Improved Synthesis of Sildenafil and Its Analogues
Sci Pharm. Methanol was added to crystallize the product and it was dried to result in compounds 4a — 4c. Compound 12c was synthesis of sildenafil citrate from compound 11c as a pale yellow solid. General Procedures: Manufactured and distributed by Cipla, Silagra is che
It is an improved version of the popular The product was collected by filtration and dried to obtain the cyclized compounds 2a — 2c. Compound 12c was prepared from compound synthesis of sildenafil citrate as a pale yellow solid.
Scheme 3. Addition of thionyl chloride as a chlorinating agent reduced the amount of unreacted sulfonic acid, compound 5and provided consistent results.
It is an improved version of the popular Secure billing. References 1.
Raghava Reddy A. Further, the pH was adjusted to 1.
We have successfully established this process on a commercial scale. Results and Discussion Chlorosulfonation is a two-stage process: Compound 14b was prepared from compound 13b.
Compound 11c was prepared from 10c as a white solid. Compound 2c was prepared from compound 14c as a white solid.